PBXIP1 Knockout ZR-75-1 Cell Line
Cat.No.:
EDJ-KZ382
Species:
Human
Cell Name:
ZR-75-1
Gene:
PBXIP1
Gene ID:
57326
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ382 |
|---|---|
| Product Name | PBXIP1 Knockout ZR75-1 Cell Line |
| Species | Human |
| Cell Line | ZR-75-1 |
| Cellosaurus ID | CVCL_0588 |
| Cell Line Synonyms | Zr-75-1, ZR751, ZR75-1, ZR75.1, ZR75_1 |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | HPIP |
| Summary |
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined. [provided by RefSeq, Dec 2015]
|
| Associated Diseases | Breast Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: ZR-75-1 | STR Info (Cell bank) Cell Line: ZR-75-1 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 11 | 10 | 11 |
| D2S1338 | 16 | 25 | 16 | 25 |
| D3S1358 | 15 | 16 | 15 | 16 |
| D5S818 | 13 | 13 | ||
| D7S820 | 10 | 11 | 10 | 11 |
| D8S1179 | 11 | 13 | 11 | 13 |
| D13S317 | 9 | 9 | ||
| D16S539 | 11 | 11 | ||
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 13 | 14 | 13 | 14 |
| D21S11 | 31 | 31 | ||
| FGA | 20 | 22 | 20 | 22 |
| Penta D | 14 | 14 | ||
| Penta E | 7 | 14 | 7 | 14 |
| TH01 | 7 | 9.3 | 7 | 9.3 |
| TPOX | 8 | 8 | ||
| vWA | 16 | 18 | 16 | 18 |
| D6S1043 | 12 | |||
| D12S391 | 21 | 21 | ||
| D2S441 | 11 | 15 | 11 | 15 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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