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PBK Knockout U2OS Cell Line

PBK Knockout U2OS Cell Line
Cat.No.:

EDJ-KZ381

Species:

Human

Cell Name:

U2OS

Gene:

PBK

Gene ID:

55872

Size:

1×10⁶cells

Cat.No. EDJ-KZ381
Product Name PBK Knockout U-2OS Cell Line
Cell Line U2OS
Cellosaurus ID CVCL_0042
Cell Line Synonyms U-2 OS, U-2OS, U-2-OS, U2-OS, U20-S, U20S, 2T
Gene
PBK
NCBI Gene ID
Gene Synonyms CT84|HEL164|Nori-3|SPK|TOPK
Summary
This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: U2OS
STR Info (Cell bank)
Cell Line: U2OS
Allele1Allele2Allele1Allele2
Amelogenin X X
CSF1PO 13 13
D1S1656 15 17.3 16 17.3
D2S1338 20 24 20 24
D3S1358 16 16
D5S818 11 11
D6S1043 11 11
D7S820 11 12 11 12
D8S1179 12 14 12 14
D12S391 19 20 19 20
D13S317 13 13
D16S539 11 12 11 12
D18S51 14 14
D19S433 15 15
D21S11 31 31
FGA 20 20
Penta D 9 9
Penta E 10 13 10 13
TH01 6 9.3 6 9.3
TPOX 11 12 11 12
VWA 14 18 14 18
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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