NCOA3 Knockout ZR-75-1 Cell Line

NCOA3 Knockout ZR-75-1 Cell Line
Cat.No.:

EDJ-KZ359

Species:

Human

Cell Name:

ZR-75-1

Gene:

NCOA3

Gene ID:

8202

Size:

1×10⁶cells

Cat.No. EDJ-KZ359
Product Name NCOA3 Knockout ZR75-1 Cell Line
Species Human
Cell Line ZR-75-1
Cellosaurus ID CVCL_0588
Cell Line Synonyms Zr-75-1, ZR751, ZR75-1, ZR75.1, ZR75_1
Gene NCOA3
NCBI Gene ID
Gene Synonyms ACTR|AIB-1|AIB1|CAGH16|CTG26|KAT13B|RAC3|SRC-3|SRC3|TNRC14|TNRC16|TRAM-1|bHLHe42|pCIP
Summary
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]
Associated Diseases Breast Carcinoma
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: ZR-75-1
STR Info (Cell bank)
Cell Line: ZR-75-1
Allele1Allele2Allele1Allele2
Amelogenin X X
CSF1PO 10 11 10 11
D2S1338 16 25 16 25
D3S1358 15 16 15 16
D5S818 13 13
D7S820 10 11 10 11
D8S1179 11 13 11 13
D13S317 9 9
D16S539 11 11
D18S51 13 14 13 14
D19S433 13 14 13 14
D21S11 31 31
FGA 20 22 20 22
Penta D 14 14
Penta E 7 14 7 14
TH01 7 9.3 7 9.3
TPOX 8 8
vWA 16 18 16 18
D6S1043 12
D12S391 21 21
D2S441 11 15 11 15
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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