NCOA3 Knockout MCF-7 Cell Line

NCOA3 Knockout MCF-7 Cell Line
Cat.No.:

EDJ-KZ358

Species:

Human

Cell Name:

MCF-7

Gene:

NCOA3

Gene ID:

8202

Size:

1×10⁶cells

Cat.No. EDJ-KZ358
Product Name NCOA3 Knockout MCF7 Cell Line
Species Human
Cell Line MCF-7
Cellosaurus ID CVCL_0031
Cell Line Synonyms MCF 7, MCF.7, MCF7, Michigan Cancer Foundation-7, ssMCF-7, ssMCF7, MCF7/WT, MCF7-CTRL, IBMF-7
Gene NCOA3
NCBI Gene ID
Gene Synonyms ACTR|AIB-1|AIB1|CAGH16|CTG26|KAT13B|RAC3|SRC-3|SRC3|TNRC14|TNRC16|TRAM-1|bHLHe42|pCIP
Summary
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: MCF-7
STR Info (Cell bank)
Cell Line: MCF-7
Allele1Allele2Allele1Allele2
Amelogenin X X
CSF1PO 10 10
D5S818 11 12 11 12
D7S820 8 9 8 9
D13S317 11 11
D16S539 11 12 11 12
TH01 6 6
TPOX 9 12 9 12
vWA 14 15 14 15
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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