MMP11 Knockout MIA PaCa-2 Cell Line
Cat.No.:
EDJ-KQ58
Species:
Human
Cell Name:
MIA PaCa-2
Gene:
MMP11
Gene ID:
4320
Size:
1×10⁶cells
MMP11 Knockout Cell Line (MIA Paca-2) is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performotion Cas9 Protein and Hassle-Free Cell Selection.
| Cat.No. | EDJ-KQ58 |
|---|---|
| Product Name | MMP11 Knockout Cell Line (MIA Paca-2) |
| Cell line | MIA PaCa-2 |
| Cellosaurus ID | CVCL_0428 |
| Cell Line Synonyms | MIA-PaCa-2, MIA-PACA-2, MIA-Pa-Ca-2, MIA Paca2, MIA PaCa2, MiaPaCa-2, MIAPACA-2, MiaPaca.2, MiaPaCa2, Miapaca2, MIAPaCa2, MIAPACA2, Mia PACA 2, MIAPaCa-2, PaCa2, MiaPaCa, MIAMI Pancreatic Carcinoma-2 |
| Gene | MMP11 |
| NCBI Gene ID | |
| Gene Synonyms | SL-3|ST3|STMY3 |
| Summary |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Pancreatic Carcinoma |
| Morphology | semi-adherent semi-suspension |
| Passage Ratio | 1:3-1:8 |
| Complete Culture Medium | 1640+10% FBS |
| Freezing Medium | 95% Complete culture medium + 5% DMSO(ATCC) |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: MIA PaCa-2 | STR Info (Cell bank) Cell Line: MIA PaCa-2 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 10 | ||
| D2S1338 | 25 | 25 | ||
| D3S1358 | 16 | 16 | ||
| D5S818 | 12 | 13 | 12 | 13 |
| D7S820 | 12 | 12 | ||
| D8S1179 | 16 | 16 | ||
| D13S317 | 12 | 13 | 12 | 13 |
| D16S539 | 10 | 13 | 10 | 13 |
| D18S51 | 12 | 12 | ||
| D19S433 | 15 | 15 | ||
| D21S11 | 29 | 31.2 | 29 | 31.2 |
| FGA | 22 | 22 | ||
| Penta D | 12 | 16 | 12 | 16 |
| Penta E | 13 | 18 | 13 | 18 |
| TH01 | 9 | 10 | 9 | 10 |
| TPOX | 9 | 9 | ||
| vWA | 15 | 15 | ||
| D6S1043 | 12 | 12 | ||
| D12S391 | 19 | 19 | ||
| D2S441 | 14 | 14 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Required Companion Kits
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