KREMEN1 Knockout RKO Cell Line
Cat.No.:
EDJ-KZ320
Species:
Human
Cell Name:
RKO
Gene:
KREMEN1
Gene ID:
83999
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ320 |
|---|---|
| Product Name | KREMEN1 Knockout RKO Cell Line |
| Cell Line | RKO |
| Cellosaurus ID | CVCL_0504 |
| Gene | KREMEN1 |
| Gene Synonyms | ECTD13|KREMEN|KRM1 |
| Summary |
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Mutations in this gene result in ectodermal dysplasia. This protein has also been found to be a functional receptor for Coxsackievirus A10 and may be an alternative entry receptor for SARS-CoV-2. [provided by RefSeq, Nov 2021]
|
| Associated Diseases | Colorectal Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: RKO | STR Info (Cell bank) Cell Line: RKO | ||||||
| Allele1 | Allele2 | Allele3 | Allele4 | Allele1 | Allele2 | Allele3 | Allele4 | |
| Amelogenin | X | X | ||||||
| CSF1PO | 8 | 10 | 8 | 10 | ||||
| D2S1338 | 16 | 16 | ||||||
| D3S1358 | 16 | 19 | 16 | 19 | ||||
| D5S818 | 11 | 13 | 11 | 13 | ||||
| D6S1043 | 13.1 | 14.1 | 19 | 20 | 14.1 | 19 | ||
| D7S820 | 8 | 10 | 8 | 10 | ||||
| D8S1179 | 9 | 13 | 14 | 9 | 13 | 14 | ||
| D12S391 | 15 | 19 | 20 | 21 | 15 | 20 | ||
| D13S317 | 8 | 11 | 8 | 11 | ||||
| D16S539 | 13 | 13 | ||||||
| D18S51 | 11 | 12 | 11 | 12 | ||||
| D19S433 | 14 | 14 | ||||||
| D21S11 | 27 | 29 | 30 | 27 | 30 | |||
| FGA | 20 | 21 | 22 | 23 | 20 | 21 | 22 | 23 |
| Penta D | 10 | 11 | 10 | 11 | ||||
| Penta E | 11 | 13 | 11 | 13 | ||||
| TH01 | 6 | 10 | 6 | 10 | ||||
| TPOX | 11 | 11 | ||||||
| vWA | 16 | 17 | 21 | 22 | 16 | 17 | 22 | |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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