HIF1A Knockout Hep-G2 Cell Line
Cat.No.:
EDJ-KZ281
Species:
Human
Cell Name:
Hep-G2
Gene:
HIF1A
Gene ID:
3091
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ281 |
|---|---|
| Product Name | HIF1A Knockout Hep G2 Cell Line |
| Cell Line | Hep-G2 |
| Cellosaurus ID | CVCL_0027 |
| Cell Line Synonyms | HEP-G2, Hep G2, HEP G2, HepG2, HEPG2 |
| Gene | HIF1A |
| Gene Synonyms | HIF-1-alpha|HIF-1A|HIF-1alpha|HIF1|HIF1-ALPHA|MOP1|PASD8|bHLHe78 |
| Summary |
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
|
| Associated Diseases | Hepatocellular Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: Hep-G2 | STR Info (Cell bank) Cell Line: Hep-G2 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1P0 | 10 | 11 | 10 | 11 |
| D2S1338 | 19 | 20 | 19 | 20 |
| D3S1358 | 15 | 16 | 15 | 16 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 10 | ||
| D8S1179 | 15 | 16 | 15 | 16 |
| D13S317 | 9 | 13 | 9 | 13 |
| D16S539 | 12 | 12 | 13 | |
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 15.2 | 15.2 | ||
| D21S11 | 29 | 31 | 29 | 31 |
| FGA | 22 | 25 | 22 | 25 |
| Penta D | 9 | 13 | 9 | 13 |
| Penta E | 15 | 20 | 15 | 20 |
| TH01 | 9 | 9 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 17 | 17 | ||
| D6S1043 | 13 | |||
| D12S391 | 21 | 25 | 21 | 25 |
| D2S441 | 11.3 | 14 | 11.3 | 14 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Required Companion Kits
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