CEBPA Knockout ZR-75-1 Cell Line
Cat.No.:
EDJ-KZ149
Species:
Human
Cell Name:
ZR-75-1
Gene:
CEBPA
Gene ID:
1050
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ149 |
|---|---|
| Product Name | CEBPA Knockout ZR75-1 Cell Line |
| Species | Human |
| Cell Line | ZR-75-1 |
| Cellosaurus ID | CVCL_0588 |
| Cell Line Synonyms | Zr-75-1, ZR751, ZR75-1, ZR75.1, ZR75_1 |
| Gene |
CEBPA
|
| NCBI Gene ID | |
| Gene Synonyms | C/EBP-alpha|CEBP |
| Summary |
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]
|
| Associated Diseases | Breast Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: ZR-75-1 | STR Info (Cell bank) Cell Line: ZR-75-1 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 11 | 10 | 11 |
| D2S1338 | 16 | 25 | 16 | 25 |
| D3S1358 | 15 | 16 | 15 | 16 |
| D5S818 | 13 | 13 | ||
| D7S820 | 10 | 11 | 10 | 11 |
| D8S1179 | 11 | 13 | 11 | 13 |
| D13S317 | 9 | 9 | ||
| D16S539 | 11 | 11 | ||
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 13 | 14 | 13 | 14 |
| D21S11 | 31 | 31 | ||
| FGA | 20 | 22 | 20 | 22 |
| Penta D | 14 | 14 | ||
| Penta E | 7 | 14 | 7 | 14 |
| TH01 | 7 | 9.3 | 7 | 9.3 |
| TPOX | 8 | 8 | ||
| vWA | 16 | 18 | 16 | 18 |
| D6S1043 | 12 | |||
| D12S391 | 21 | 21 | ||
| D2S441 | 11 | 15 | 11 | 15 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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