Ythdf1 Knockout MC-38 Cell Line
Cat.No.:
EDJ-KZ85
Species:
Mouse
Cell Name:
MC-38
Gene:
Ythdf1
Gene ID:
54915
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ85 |
|---|---|
| Product Name | Ythdf1 Knockout MC38 Cell Line |
| Species | Mouse |
| Cell Line | MC-38 |
| Cellosaurus ID | CVCL_B288 |
| Cell Line Synonyms | MCA-38, MCA 38, MCA38, MC38, MC-38 B/6, Mouse Colon 38, Murine Carcinoma-38, Colon-38, Colon 38, Colon38, C38 |
| Gene | Ythdf1 |
| Gene Synonyms | C20orf21|DF1 |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: MC-38 | STR Info (Cell bank) Cell Line: MC-38 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| 1-1 | 16 | 16 | ||
| 1-2 | 19 | 19 | ||
| 2-1 | 16 | 16 | ||
| 3-2 | 13 | 14 | 13 | 14 |
| 4-2 | 20.3 | 20.3 | ||
| 5-5 | 17 | 17 | ||
| 6-4 | 18 | 18 | ||
| 6-7 | 14 | 15 | 14 | 15 |
| 7-1 | 26.2 | 26.2 | ||
| 8-1 | 16 | 17 | 16 | 17 |
| 11-2 | 16 | 16 | ||
| 12-1 | 17 | 17 | ||
| 13-1 | 17.1 | 17.1 | ||
| 15-3 | 22.3 | 22.3 | ||
| 17-2 | 15 | 15 | ||
| 18-3 | 16 | 16 | ||
| 19-2 | 13 | 13 | ||
| X-1 | 27 | 27 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Related Publications
Targeting mA reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer.
IF=25.8
Gut
This KO model may be useful for:
- Investigating the role of YTHDF1 in m⁶A-mediated post-transcriptional regulation in colorectal cancer
- Studying the impact of YTHDF1 loss on antitumour immunity and immune checkpoint blockade response
- Evaluating YTHDF1 as a potential target for enhancing anti-PD-1 immunotherapy efficacy
- Functional assays to assess YTHDF1-dependent modulation of tumour-immune microenvironment
- Preclinical screening of combination therapies involving YTHDF1 inhibition and immune checkpoint inhibitors
Required Accessories
Cell Culture Optimization Series
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