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WWOX Knockout iPSC Cell Line
Cat.No.:
EDJ-KZ81
Species:
Human
Cell Name:
iPSC
Gene:
WWOX
Gene ID:
51741
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ81 |
|---|---|
| Product Name | WWOX Knockout iPSC Cell Line |
| Species | Human |
| Cell Line | iPSC |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | D16S432E|DEE28|EIEE28|FOR|FRA16D|HHCMA56|PRO0128|SCAR12|SDR41C1|WOX1 |
| Summary |
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
|
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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