TNXB Knockout KYSE-30 Cell Line
Cat.No.:
EDJ-KZ57
Species:
Human
Cell Name:
KYSE-30
Gene:
TNXB
Gene ID:
7148
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ57 |
|---|---|
| Product Name | TNXB Knockout KYSE-30 Cell Line |
| Cell Line | KYSE-30 |
| Cellosaurus ID | CVCL_1351 |
| Cell Line Synonyms | Kyse-30, KYSE 30, KYSE30, Kyse30, KYSE0030 |
| Gene | TNXB |
| Gene Synonyms | EDS3|EDSCLL|EDSCLL1|HXBL|TENX|TN-X|TNX|TNXB1|TNXB2|TNXBS|VUR8|XB|XBS |
| Summary |
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Esophageal Squamous Cell Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: KYSE-30 | STR Info (Cell bank) Cell Line: KYSE-30 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| Amelogenin | X | X | ||||
| CSF1PO | 10 | 10 | ||||
| D2S1338 | 23 | 23 | ||||
| D3S1358 | 15 | 16 | 15 | 16 | ||
| D5S818 | 11 | 11 | ||||
| D7S820 | 11 | 11.3 | 11 | 11.3 | ||
| D8S1179 | 12 | 15 | 12 | 15 | ||
| D13S317 | 9 | 9 | ||||
| D16S539 | 10 | 12 | 10 | 12 | ||
| D18S51 | 14 | 14 | ||||
| D19S433 | 14.2 | 15.2 | 15 | 16 | ||
| D21S11 | 28 | 28 | ||||
| FGA | 24 | 24 | ||||
| Penta D | 12 | 12 | ||||
| Penta E | 13 | 13 | ||||
| TH01 | 9 | 9 | ||||
| TPOX | 9 | 9 | ||||
| vWA | 16 | 18 | 19 | 16 | 18 | 19 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.