TNXB Knockout KYSE-30 Cell Line

TNXB Knockout KYSE-30 Cell Line
Cat.No.:

EDJ-KZ57

Species:

Human

Cell Name:

KYSE-30

Gene:

TNXB

Gene ID:

7148

Size:

1×10⁶cells

Cat.No. EDJ-KZ57
Product Name TNXB Knockout KYSE-30 Cell Line
Cell Line KYSE-30
Cellosaurus ID CVCL_1351
Cell Line Synonyms Kyse-30, KYSE 30, KYSE30, Kyse30, KYSE0030
Gene TNXB
Gene Synonyms EDS3|EDSCLL|EDSCLL1|HXBL|TENX|TN-X|TNX|TNXB1|TNXB2|TNXBS|VUR8|XB|XBS
Summary
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Associated Diseases Esophageal Squamous Cell Carcinoma
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: KYSE-30
STR Info (Cell bank)
Cell Line: KYSE-30
Allele1Allele2Allele3Allele1Allele2Allele3
Amelogenin X X
CSF1PO 10 10
D2S1338 23 23
D3S1358 15 16 15 16
D5S818 11 11
D7S820 11 11.3 11 11.3
D8S1179 12 15 12 15
D13S317 9 9
D16S539 10 12 10 12
D18S51 14 14
D19S433 14.2 15.2 15 16
D21S11 28 28
FGA 24 24
Penta D 12 12
Penta E 13 13
TH01 9 9
TPOX 9 9
vWA 16 18 19 16 18 19
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

Required Accessories

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