SPPL2A Knockout A-549 Cell Line

SPPL2A Knockout A-549 Cell Line
Cat.No.:

EDJ-KQ37417

Species:

Human

Cell Name:

A-549

Gene:

SPPL2A

Gene ID:

84888

Size:

1×10⁶cells

SPPL2A Knockout Cell Line (A549) is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performance Cas9 Protein and Hassle-Free Cell Selection.
Cat.No. EDJ-KQ37417
Product Name SPPL2A Knockout A549 Cell Line
Cell Line A-549
Cellosaurus ID CVCL_0023
Cell Line Synonyms A 549, A549, NCI-A549, A549/ATCC, A549 ATCC, A549ATCC, hA549
Gene
NCBI Gene ID
Gene Synonyms IMD86|IMP3|PSL2
Summary
This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012]
Associated Diseases Non-Small Cell Lung Carcinoma
Morphology Adherent
Passage Ratio 1/5-1/4 ,2days
Complete Culture Medium F-12K + 10% FBS
Freezing Medium 95% Complete culture medium + 5% DMSO
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: A-549
STR Info (Cell bank)
Cell Line: A-549
Allele1Allele2Allele1Allele2
Amelogenin X Y X Y
CSF1PO 10 12 10 12
D2S1338 24 24
D3S1358 16 16
D5S818 11 11
D7S820 8 11 8 11
D8S1179 13 14 13 14
D13S317 11 11
D16S539 11 12 11 12
D18S51 14 17 14 17
D19S433 13 13
D21S11 29 29
FGA 23 23
Penta D 9 9
Penta E 7 11 7 11
TH01 8 9.3 8 9.3
TPOX 8 11 8 11
vWA 14 14
D6S1043 11 13
D12S391 18 18
D2S441 10 13 10 13
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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