SOCS1 Knockout BEAS-2B Cell Line
Cat.No.:
EDJ-KZ486
Species:
Human
Cell Name:
BEAS-2B
Gene:
SOCS1
Gene ID:
8651
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ486 |
|---|---|
| Product Name | SOCS1 Knockout BEAS-2B Cell Line |
| Cell Line | BEAS-2B |
| Cellosaurus ID | CVCL_0168 |
| Cell Line Synonyms | Beas-2B, BEAS 2B, BEAS2B, Beas2B, Bronchial Epithelium transformed with Ad12-SV40 2B |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | AISIMD|CIS1|CISH1|JAB|SOCS-1|SSI-1|SSI1|TIP-3|TIP3 |
| Summary |
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: BEAS-2B | STR Info (Cell bank) Cell Line: BEAS-2B | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| D5S818 | 12 | 13 | 12 | 13 |
| D13S317 | 13 | 13 | ||
| D7S820 | 10 | 13 | 10 | 13 |
| D16S539 | 12 | 12 | ||
| vWA | 17 | 18 | 17 | 18 |
| TH01 | 7 | 9.3 | 7 | 9.3 |
| TPOX | 6 | 11 | 6 | 11 |
| CSF1PO | 9 | 12 | 9 | 12 |
| D19S433 | 13.2 | 15.2 | 13.2 | 15.2 |
| D21S11 | 28 | 30 | 28 | 30 |
| D18S51 | 18 | 19 | 18 | 19 |
| D6S1043 | 12 | 18 | ||
| D3S1358 | 15 | 17 | 15 | 17 |
| Penta D | 2.2 | 13 | 2.2 | 13 |
| D2S441 | 11 | 11.3 | 11 | 11.3 |
| D8S1179 | 13 | 15 | 13 | 15 |
| Penta E | 5 | 8 | 5 | 8 |
| D12S391 | 17 | 18 | 17 | 18 |
| D2S1338 | 22 | 23 | 22 | 23 |
| FGA | 20 | 24 | 20 | 24 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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