SHMT1 Knockout PK-15 Cell Line

SHMT1 Knockout PK-15 Cell Line
Cat.No.:

EDJ-KZ454

Species:

Pig

Cell Name:

PK-15

Gene:

SHMT1

Gene ID:

6470

Size:

1×10⁶cells

Cat.No. EDJ-KZ454
Product Name SHMT1 Knockout PK-15 Cell Line
Species Pig
Cell Line PK-15
Cellosaurus ID CVCL_2160
Cell Line Synonyms PK(15), PK (15), PK 15, PK15, Porcine Kidney-15
Gene SHMT1
Gene Synonyms CSHMT|SHMT
Summary
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Associated Diseases Non-tumor
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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