SHMT1 Knockout PK-15 Cell Line
Cat.No.:
EDJ-KZ454
Species:
Pig
Cell Name:
PK-15
Gene:
SHMT1
Gene ID:
6470
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ454 |
|---|---|
| Product Name | SHMT1 Knockout PK-15 Cell Line |
| Species | Pig |
| Cell Line | PK-15 |
| Cellosaurus ID | CVCL_2160 |
| Cell Line Synonyms | PK(15), PK (15), PK 15, PK15, Porcine Kidney-15 |
| Gene |
SHMT1 |
| Gene Synonyms | CSHMT|SHMT |
| Summary |
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
|
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.