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SETD2 Knockout CNE-1 Cell Line
Cat.No.:
EDJ-KZ450
Species:
Human
Cell Name:
CNE-1
Gene:
SETD2
Gene ID:
29072
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ450 |
|---|---|
| Product Name | SETD2 Knockout CNE1 Cell Line |
| Cell Line | CNE-1 |
| Cellosaurus ID | CVCL_6888 |
| Cell Line Synonyms | CNE1, CNE |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | HBP231|HIF-1|HIP-1|HSPC069|HYPB|KMT3A|LLS|MRD70|RAPAS|SET2|p231HBP |
| Summary |
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
|
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.