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SETD2 Knockout CNE-1 Cell Line

SETD2 Knockout CNE-1 Cell Line
Cat.No.:

EDJ-KZ450

Species:

Human

Cell Name:

CNE-1

Gene:

SETD2

Gene ID:

29072

Size:

1×10⁶cells

Cat.No. EDJ-KZ450
Product Name SETD2 Knockout CNE1 Cell Line
Cell Line CNE-1
Cellosaurus ID CVCL_6888
Cell Line Synonyms CNE1, CNE
Gene
NCBI Gene ID
Gene Synonyms HBP231|HIF-1|HIP-1|HSPC069|HYPB|KMT3A|LLS|MRD70|RAPAS|SET2|p231HBP
Summary
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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