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RPL13A Knockout A-549 Cell Line

RPL13A Knockout A-549 Cell Line

RPL13A Knockout Cell Line (A549) is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performance Cas9 Protein and Hassle-Free Cell Selection.

Cat. No EDJ-KQ64256
Species Human
Cell Line A-549
Gene RPL13A
Size 1×10⁶ cells

Product Details

Cat.No. EDJ-KQ64256 Product Name RPL13A Knockout A549 Cell Line
Cell Line A-549 Cellosaurus ID CVCL_0023
Cell Line Synonyms A 549, A549, NCI-A549, A549/ATCC, A549 ATCC, A549ATCC, hA549 Gene
NCBI Gene ID Gene Synonyms L13A|TSTA1|uL13
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L13P family of ribosomal proteins that is a component of the 60S subunit. The encoded protein also plays a role in the repression of inflammatory genes as a component of the IFN-gamma-activated inhibitor of translation (GAIT) complex. This gene is co-transcribed with the small nucleolar RNA genes U32, U33, U34, and U35, which are located in the second, fourth, fifth, and sixth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Associated Diseases Non-Small Cell Lung Carcinoma
Morphology Adherent Passage Ratio 1/5-1/4, 2days
Complete Culture Medium F-12K + 10% FBS Freezing Medium 95% Complete culture medium + 5% DMSO
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.

STR Profile

LociSTR Info (Sample Cell)
Sample Cell Line: A-549
STR Info (Cell bank)
Cell Line: A-549
Allele1Allele2Allele1Allele2
Amelogenin X Y X Y
CSF1PO 10 12 10 12
D2S1338 24 24
D3S1358 16 16
D5S818 11 11
D7S820 8 11 8 11
D8S1179 13 14 13 14
D13S317 11 11
D16S539 11 12 11 12
D18S51 14 17 14 17
D19S433 13 13
D21S11 29 29
FGA 23 23
Penta D 9 9
Penta E 7 11 7 11
TH01 8 9.3 8 9.3
TPOX 8 11 8 11
vWA 14 14
D6S1043 11 13
D12S391 18 18
D2S441 10 13 10 13
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
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