RBKS Knockout K-562 Cell Line
Cat.No.:
EDJ-KZ426
Species:
Human
Cell Name:
K-562
Gene:
RBKS
Gene ID:
64080
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ426 |
|---|---|
| Product Name | RBKS Knockout K-562 Cell Line |
| Species | Human |
| Cell Line | K-562 |
| Cellosaurus ID | CVCL_U226 |
| Gene | RBKS |
| Gene Synonyms | RBSK|RK |
| Summary |
This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
|
| Associated Diseases | Chronic Myelogenous Leukemia |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: K-562 | STR Info (Cell bank) Cell Line: K-562 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1P0 | 9 | 10 | 9 | 10 |
| D2S1338 | 17 | 17 | ||
| D3S1358 | 16 | 16 | ||
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 9 | 11 | 9 | 11 |
| D8S1179 | 12 | 12 | ||
| D13S317 | 8 | 8 | ||
| D16S539 | 11 | 12 | 11 | 12 |
| D18S51 | 15 | 16 | 15 | 16 |
| D19S433 | 14 | 14.2 | 14 | 14.2 |
| D21S11 | 29 | 31 | 29 | 31 |
| FGA | 21 | 24 | 21 | 24 |
| Penta D | 9 | 13 | 9 | 13 |
| Penta E | 5 | 14 | 5 | 14 |
| TH01 | 9.3 | 9.3 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 16 | 16 | ||
| D6S1043 | 11 | |||
| D12S391 | 23 | 23 | ||
| D2S441 | 10 | 14 | 10 | 14 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Related Publications
D-ribose-induced cytotoxicity in K562 cells: RBKS-dependent disruption of copper homeostasis and mitochondrial function.
IF=8.2
Free radical biology & medicine
This KO model may be useful for:
- Investigating RBKS-dependent copper homeostasis and mitochondrial dysfunction
- Studying D-ribose-induced cytotoxicity and metabolic stress responses
- Evaluating the role of RBKS in redox balance and apoptosis pathways
- Screening for therapeutic targets in ribose metabolism-related disorders
- Functional validation of RBKS in nucleotide salvage and energy metabolism
Required Accessories
Cell Culture Optimization Series
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