OVOL2 Knockout MCF-7 Cell Line

OVOL2 Knockout MCF-7 Cell Line
Cat.No.:

EDJ-KZ38

Species:

Human

Cell Name:

MCF-7

Gene:

OVOL2

Gene ID:

58495

Size:

1×10⁶cells

Cat.No. EDJ-KZ38
Product Name OVOL2 Knockout MCF7 Cell Line
Species Human
Cell Line MCF-7
Cellosaurus ID CVCL_0031
Cell Line Synonyms MCF 7, MCF.7, MCF7, Michigan Cancer Foundation-7, ssMCF-7, ssMCF7, MCF7/WT, MCF7-CTRL, IBMF-7
Gene
NCBI Gene ID
Gene Synonyms CHED|CHED1|CHED2|EUROIMAGE566589|PPCD1|ZNF339
Summary
This gene encodes a member of the evolutionarily conserved ovo-like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N- and C-terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion, impaired vascularization, and heart anomalies. In humans, allelic variants of this gene have been associated with posterior polymorphous corneal dystrophy. [provided by RefSeq, Apr 2016]
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: MCF-7
STR Info (Cell bank)
Cell Line: MCF-7
Allele1Allele2Allele1Allele2
Amelogenin X X
CSF1PO 10 10
D5S818 11 12 11 12
D7S820 8 9 8 9
D13S317 11 11
D16S539 11 12 11 12
TH01 6 6
TPOX 9 12 9 12
vWA 14 15 14 15
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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