NR1H4 Knockout Huh-7 Cell Line
Cat.No.:
EDJ-KZ374
Species:
Human
Cell Name:
Huh-7
Gene:
NR1H4
Gene ID:
9971
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ374 |
|---|---|
| Product Name | NR1H4 Knockout Huh-7 Cell Line |
| Cell Line | Huh-7 |
| Cellosaurus ID | CVCL_0336 |
| Cell Line Synonyms | HuH-7, HUH-7, HuH7, Huh7, HUH7, HUH7.0, JTC-39, Japanese Tissue Culture-39 |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | BAR|FXR|HRR-1|HRR1|PFIC5|RIP14 |
| Summary |
This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]
|
| Associated Diseases | Hepatocellular Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: Huh-7 | STR Info (Cell bank) Cell Line: Huh-7 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1P0 | 11 | 11 | ||
| D2S1338 | 19 | 19 | ||
| D3S1358 | 15 | 15 | ||
| D5S818 | 12 | 12 | ||
| D7S820 | 11 | 11 | ||
| D8S1179 | 14 | 14 | 15 | |
| D13S317 | 10 | 11 | 10 | 11 |
| D16S539 | 10 | 10 | ||
| D18S51 | 15 | 15 | ||
| D19S433 | 13 | 14 | 13 | 14 |
| D21S11 | 30 | 30 | ||
| FGA | 22 | 23 | 22 | 23 |
| Penta D | 12 | 12 | ||
| Penta E | 11 | 11 | ||
| TH01 | 7 | 7 | ||
| TPOX | 8 | 11 | 8 | 11 |
| vWA | 16 | 18 | 16 | 18 |
| D6S1043 | 13 | 15 | 13 | 15 |
| D12S391 | 20 | 21 | 20 | 21 |
| D2S441 | 12 | 14 | 12 | 14 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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