MAGEA4 Knockout A-375 Cell Line
Cat.No.:
EDJ-KQ18108
Species:
Human
Cell Name:
A-375
Gene:
MAGEA4
Gene ID:
4103
Size:
1×10⁶cells
MAGEA4 Knockout A-375 Cell Line is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performotion Cas9 Protein and Hassle-Free Cell Selection.
| Cat.No. | EDJ-KQ18108 |
|---|---|
| Product Name | MAGEA4 Knockout A-375 Cell Line |
| Cell Line | A-375 |
| Cellosaurus ID | CVCL_0132 |
| Cell Line Synonyms | A 375, A375, A375-MEL, A375-mel, A375mel, 375 |
| Gene |
MAGEA4
|
| NCBI Gene ID | |
| Gene Synonyms | CT1.4|MAGE-41|MAGE-X2|MAGE4|MAGE4A|MAGE4B |
| Summary |
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020]
|
| Associated Diseases | Melanoma |
| Morphology | Adherent |
| Passage Ratio | 1/4-1/3,2 days |
| Complete Culture Medium | DMEM+10% FBS+1% GlutaMax |
| Freezing Medium | 95%Complete culture medium+5% DMSO |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: A-375 | STR Info (Cell bank) Cell Line: A-375 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 11 | 12 | 11 | 12 |
| D2S1338 | 16 | 24 | 16 | 24 |
| D3S1358 | 15 | 17 | 15 | 17 |
| D5S818 | 12 | 12 | ||
| D7S820 | 9 | 9 | ||
| D8S1179 | 11 | 14 | 11 | 14 |
| D13S317 | 11 | 14 | 11 | 14 |
| D16S539 | 9 | 9 | ||
| D18S51 | 12 | 17 | 12 | 17 |
| D19S433 | 13 | 14.2 | 13 | 14.2 |
| D21S11 | 29 | 30 | 29 | 30 |
| FGA | 23 | 23 | ||
| Penta D | 9 | 15 | 9 | 15 |
| Penta E | 10 | 12 | 10 | 12 |
| TH01 | 8 | 8 | ||
| TPOX | 8 | 10 | 8 | 10 |
| vWA | 16 | 17 | 16 | 17 |
| D6S1043 | 11 | 14 | ||
| D12S391 | 18 | 21 | 18 | 21 |
| D2S441 | 11 | 11 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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