LentiCRISPR v2-sgRNA design for SERPINE1 TF binding site-sgRNA2-puro
EDITGENE guarantees LentiCRISPR v2-sgRNA design for SERPINE1 TF binding site-sgRNA2-puro plasmid has passed QC, endotoxin-free, and project validated.
Product Details
| Plasmid Resistance | Amp | Type | KO |
|---|---|---|---|
| Selection Marker | puro | Tag | / |
| Gene ID | Gene | ||
| Gene Synonyms | PAI|PAI-1|PAI1|PLANH1 | Summary |
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020]
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* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
Storage
Store at -20 ºC for short term. -80 ºC for long term preservation.
