LRBA Knockout Jurkat Cell Line

LRBA Knockout Jurkat Cell Line
Cat.No.:

EDJ-KZ338

Species:

Human

Cell Name:

Jurkat

Gene:

LRBA

Gene ID:

987

Size:

1×10⁶cells

Cat.No. EDJ-KZ338
Product Name LRBA Knockout Jurkat Cell Line
Cell Line Jurkat
Cellosaurus ID CVCL_0065
Cell Line Synonyms JURKAT, JM, JM-Jurkat, Jurkat-FHCRC, Jurkat FHCRC, FHCRC-11, FHCRC subclone 11, FCCH1024
Gene LRBA
Gene Synonyms BGL|CDC4L|CVID8|LAB300|LBA|uc.147
Summary
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: Jurkat
STR Info (Cell bank)
Cell Line: Jurkat
Allele1Allele2Allele3Allele4Allele1Allele2Allele3Allele4
Amelogenin X Y X Y
CSF1PO 9 10 11 9 10 11
CSF1PO 10 11 10 11
CSF1PO 10 12 10 12
CSF1PO 11 11
CSF1PO 11 12 11 12
D2S1338 19 23 19 23
D2S1338 19 23 24 19 23 24
D3S1358 15 15
D3S1358 15 16 17 15 16 17
D3S1358 15 17 15 17
D5S818 9 9
D7S820 8 10 8 10
D7S820 8 10 11 8 10 11
D7S820 8 12 8 12
D8S1179 12 14 15 12 14 15
D8S1179 13 13
D8S1179 13 14 13 14
D13S317 8 10 11 8 10 11
D13S317 8 11 8 11
D13S317 8 11 12 8 11 12
D13S317 8 12 8 12
D16S539 10 11 10 11
D16S539 11 11
D18S51 13 14 20 21 13 14 20 21
D18S51 13 21 13 21
D19S433 13 15.2 13 15.2
D19S433 13 16 13 16
D19S433 14 15.2 14 15.2
D21S11 31.2 32.2 31.2 32.2
D21S11 31.2 32.2 33.2 31.2 32.2 33.2
D21S11 31.2 33.2 31.2 33.2
FGA 20 21 20 21
FGA 20 21 22 20 21 22
FGA 20 22 20 22
Penta D 11 13 11 13
Penta E 9 10 12 9 10 12
Penta E 10 12 10 12
TH01 6 9.3 6 9.3
TPOX 8 9 10 8 9 10
TPOX 8 10 8 10
vWA 16 17 18 16 17 18
vWA 16 17 19 20 16 17 19 20
vWA 17 18 19 17 18 19
vWA 17 18 19 20 17 18 19 20
vWA 18 18
vWA 18 19 20 18 19 20
vWA 18 20 18 20
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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