KRAS Knockout RKO Cell Line
Cat.No.:
EDJ-KZ319
Species:
Human
Cell Name:
RKO
Gene:
KRAS
Gene ID:
3845
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ319 |
|---|---|
| Product Name | KRAS Knockout RKO Cell Line |
| Cell Line | RKO |
| Cellosaurus ID | CVCL_0504 |
| Gene | KRAS |
| Gene Synonyms | 'C-K-RAS|C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|K-Ras|K-Ras 2|KI-RAS|KRAS1|KRAS2|NS|NS3|OES|RALD|RASK2|c-Ki-ras|c-Ki-ras2 |
| Summary |
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Colorectal Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: RKO | STR Info (Cell bank) Cell Line: RKO | ||||||
| Allele1 | Allele2 | Allele3 | Allele4 | Allele1 | Allele2 | Allele3 | Allele4 | |
| Amelogenin | X | X | ||||||
| CSF1PO | 8 | 10 | 8 | 10 | ||||
| D2S1338 | 16 | 16 | ||||||
| D3S1358 | 16 | 19 | 16 | 19 | ||||
| D5S818 | 11 | 13 | 11 | 13 | ||||
| D6S1043 | 13.1 | 14.1 | 19 | 20 | 14.1 | 19 | ||
| D7S820 | 8 | 10 | 8 | 10 | ||||
| D8S1179 | 9 | 13 | 14 | 9 | 13 | 14 | ||
| D12S391 | 15 | 19 | 20 | 21 | 15 | 20 | ||
| D13S317 | 8 | 11 | 8 | 11 | ||||
| D16S539 | 13 | 13 | ||||||
| D18S51 | 11 | 12 | 11 | 12 | ||||
| D19S433 | 14 | 14 | ||||||
| D21S11 | 27 | 29 | 30 | 27 | 30 | |||
| FGA | 20 | 21 | 22 | 23 | 20 | 21 | 22 | 23 |
| Penta D | 10 | 11 | 10 | 11 | ||||
| Penta E | 11 | 13 | 11 | 13 | ||||
| TH01 | 6 | 10 | 6 | 10 | ||||
| TPOX | 11 | 11 | ||||||
| vWA | 16 | 17 | 21 | 22 | 16 | 17 | 22 | |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Required Companion Kits
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