ITGAM Knockout BEAS-2B Cell Line
Cat.No.:
EDJ-KZ300
Species:
Human
Cell Name:
BEAS-2B
Gene:
ITGAM
Gene ID:
3684
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ300 |
|---|---|
| Product Name | ITGAM Knockout BEAS-2B Cell Line |
| Cell Line | BEAS-2B |
| Cellosaurus ID | CVCL_0168 |
| Cell Line Synonyms | Beas-2B, BEAS 2B, BEAS2B, Beas2B, Bronchial Epithelium transformed with Ad12-SV40 2B |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | CD11B|CR3A|MAC-1|MAC1A|MO1A|SLEB6 |
| Summary |
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
|
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: BEAS-2B | STR Info (Cell bank) Cell Line: BEAS-2B | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| D5S818 | 12 | 13 | 12 | 13 |
| D13S317 | 13 | 13 | ||
| D7S820 | 10 | 13 | 10 | 13 |
| D16S539 | 12 | 12 | ||
| vWA | 17 | 18 | 17 | 18 |
| TH01 | 7 | 9.3 | 7 | 9.3 |
| TPOX | 6 | 11 | 6 | 11 |
| CSF1PO | 9 | 12 | 9 | 12 |
| D19S433 | 13.2 | 15.2 | 13.2 | 15.2 |
| D21S11 | 28 | 30 | 28 | 30 |
| D18S51 | 18 | 19 | 18 | 19 |
| D6S1043 | 12 | 18 | ||
| D3S1358 | 15 | 17 | 15 | 17 |
| Penta D | 2.2 | 13 | 2.2 | 13 |
| D2S441 | 11 | 11.3 | 11 | 11.3 |
| D8S1179 | 13 | 15 | 13 | 15 |
| Penta E | 5 | 8 | 5 | 8 |
| D12S391 | 17 | 18 | 17 | 18 |
| D2S1338 | 22 | 23 | 22 | 23 |
| FGA | 20 | 24 | 20 | 24 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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