IRGM Knockout U-251MG Cell Line
Cat.No.:
EDJ-KZ30
Species:
Human
Cell Name:
U-251MG
Gene:
IRGM
Gene ID:
345611
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ30 |
|---|---|
| Product Name | IRGM Knockout U-251 MG Cell Line |
| Species | Human |
| Cell Line | U-251MG |
| Cellosaurus ID | CVCL_0021 |
| Cell Line Synonyms | U-251 MG, U-251-MG, U-251_MG, U251-MG, U251MG, U-251, U251, U251n, U251N, 251 MG, 251MG, 251 MG(6) |
| Gene |
IRGM
|
| NCBI Gene ID | |
| Gene Synonyms | IBD19|IFI1|IRGM1|LRG-47|LRG47 |
| Summary |
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
|
| Associated Diseases | Glioma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: U-251MG | STR Info (Cell bank) Cell Line: U-251MG | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 11 | 12 | 11 | 12 |
| D2S1338 | 22 | 24 | 22 | 24 |
| D3S1358 | 16 | 17 | 16 | 17 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 12 | 10 | 12 |
| D8S1179 | 13 | 15 | 13 | 15 |
| D13S317 | 10 | 11 | 10 | 11 |
| D16S539 | 12 | 12 | ||
| D18S51 | 13 | 13 | ||
| D19S433 | 13 | 15 | 13 | 15 |
| D21S11 | 29 | 29 | ||
| FGA | 21 | 25 | 21 | 25 |
| Penta D | 12 | 12 | ||
| Penta E | 7 | 10 | 7 | 10 |
| TH01 | 9.3 | 9.3 | ||
| TPOX | 8 | 8 | ||
| vWA | 16 | 18 | 16 | 18 |
| D6S1043 | 12 | |||
| D12S391 | 17 | 22 | ||
| D2S441 | 11 | |||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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