IL17RA Knockout MIA PaCa-2 Cell Line
Cat.No.:
EDJ-KZ297
Species:
Human
Cell Name:
MIA PaCa-2
Gene:
IL17RA
Gene ID:
23765
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ297 |
|---|---|
| Product Name | IL17RA Knockout MIA-PACA2 Cell Line |
| Species | Human |
| Cell Line | MIA PaCa-2 |
| Cellosaurus ID | CVCL_0428 |
| Cell Line Synonyms | MIA-PaCa-2, MIA-PACA-2, MIA-Pa-Ca-2, MIA Paca2, MIA PaCa2, MiaPaCa-2, MIAPACA-2, MiaPaca.2, MiaPaCa2, Miapaca2, MIAPaCa2, MIAPACA2, Mia PACA 2, MIAPaCa-2, PaCa2, MiaPaCa, MIAMI Pancreatic Carcinoma-2 |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | CANDF5|CD217|CDw217|IL-17RA|IL17R|IMD51|hIL-17R |
| Summary |
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
|
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: MIA PaCa-2 | STR Info (Cell bank) Cell Line: MIA PaCa-2 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 10 | ||
| D2S1338 | 25 | 25 | ||
| D3S1358 | 16 | 16 | ||
| D5S818 | 12 | 13 | 12 | 13 |
| D7S820 | 12 | 12 | ||
| D8S1179 | 16 | 16 | ||
| D13S317 | 12 | 13 | 12 | 13 |
| D16S539 | 10 | 13 | 10 | 13 |
| D18S51 | 12 | 12 | ||
| D19S433 | 15 | 15 | ||
| D21S11 | 29 | 31.2 | 29 | 31.2 |
| FGA | 22 | 22 | ||
| Penta D | 12 | 16 | 12 | 16 |
| Penta E | 13 | 18 | 13 | 18 |
| TH01 | 9 | 10 | 9 | 10 |
| TPOX | 9 | 9 | ||
| vWA | 15 | 15 | ||
| D6S1043 | 12 | 12 | ||
| D12S391 | 19 | 19 | ||
| D2S441 | 14 | 14 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.