Gpx4 Knockout RAW 264.7 Cell Line
Cat.No.:
EDJ-KZ27
Species:
Mouse
Cell Name:
RAW 264.7
Gene:
Gpx4
Gene ID:
625249
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ27 |
|---|---|
| Product Name | Gpx4 Knockout RAW 264.7 Cell Line |
| Cell Line | RAW 264.7 |
| Cellosaurus ID | CVCL_0493 |
| Cell Line Synonyms | RAW264, RAW2647, RAW264.7, RAW-264.7, Raw 264.7, Raw264.7 |
| Gene |
Gpx4
|
| NCBI Gene ID | |
| Gene Synonyms | GPx-4|GSHPx-4|MCSP|PHGPx|SMDS|snGPx|snPHGPx |
| Associated Diseases | Leukemia |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: RAW 264.7 | STR Info (Cell bank) Cell Line: RAW 264.7 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| 1-1 | 16 | 15 | 16 | |
| 1-2 | 17 | 17 | ||
| 2-1 | 16 | 16 | ||
| 3-2 | 14 | 14 | ||
| 4-2 | 22.3 | 22.3 | ||
| 5-5 | 14 | 15 | 14 | |
| 6-4 | 17 | 18 | 18 | |
| 6-7 | 12 | 13 | 12 | |
| 7-1 | 25.2 | 25.2 | ||
| 8-1 | 13 | 13 | ||
| 11-2 | 17 | 17 | ||
| 12-1 | 16 | 16 | ||
| 13-1 | 16.2 | 16.2 | ||
| 15-3 | 22.3 | 22.3 | ||
| 17-2 | 14 | 16 | 14 | 16 |
| 18-3 | 18 | 18 | ||
| 19-2 | 14 | 14 | ||
| X-1 | 24 | 24 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Research Publications
Extracellular vesicle-packaged GBP2 from macrophages aggravates sepsis-induced acute lung injury by promoting ferroptosis in pulmonary vascular endothelial cells.
IF=11.9
Redox biology
Tartrate-Resistant Acid Phosphatase 5 (TRAP/ACP5) aggravates atherosclerosis by regulating macrophage polarization and promoting ferroptosis.
IF=8.2
Free radical biology & medicine
Myeloid zinc finger 1 knockdown promotes osteoclastogenesis and bone loss in part by regulating RANKL-induced ferroptosis of osteoclasts through Nrf2/GPX4 signaling pathway.
IF=3.1
Journal of leukocyte biology
This KO model may be useful for:
- Investigating the role of GPX4-mediated ferroptosis in macrophage-driven inflammatory diseases
- Studying macrophage polarization and its contribution to atherosclerosis
- Exploring ferroptosis-dependent mechanisms in sepsis-induced acute lung injury
- Evaluating therapeutic interventions targeting ferroptosis in vascular endothelial cell damage
- Functional validation of GPX4 in extracellular vesicle-mediated intercellular signaling
Recommended Accessories
Cell Culture Optimization Series
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