FGA Knockout Hep-G2 Cell Line
Cat.No.:
EDJ-KZ250
Species:
Human
Cell Name:
Hep-G2
Gene:
FGA
Gene ID:
2243
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ250 |
|---|---|
| Product Name | FGA Knockout Hep G2 Cell Line |
| Cell Line | Hep-G2 |
| Cellosaurus ID | CVCL_0027 |
| Cell Line Synonyms | HEP-G2, Hep G2, HEP G2, HepG2, HEPG2 |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | AMYLD2|Fib2 |
| Summary |
This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. [provided by RefSeq, Jan 2016]
|
| Associated Diseases | Hepatocellular Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: Hep-G2 | STR Info (Cell bank) Cell Line: Hep-G2 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1P0 | 10 | 11 | 10 | 11 |
| D2S1338 | 19 | 20 | 19 | 20 |
| D3S1358 | 15 | 16 | 15 | 16 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 10 | ||
| D8S1179 | 15 | 16 | 15 | 16 |
| D13S317 | 9 | 13 | 9 | 13 |
| D16S539 | 12 | 12 | 13 | |
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 15.2 | 15.2 | ||
| D21S11 | 29 | 31 | 29 | 31 |
| FGA | 22 | 25 | 22 | 25 |
| Penta D | 9 | 13 | 9 | 13 |
| Penta E | 15 | 20 | 15 | 20 |
| TH01 | 9 | 9 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 17 | 17 | ||
| D6S1043 | 13 | |||
| D12S391 | 21 | 25 | 21 | 25 |
| D2S441 | 11.3 | 14 | 11.3 | 14 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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