FAP Knockout U-87MG ATCC Cell Line
Cat.No.:
EDJ-KZ24
Species:
Human
Cell Name:
U-87MG ATCC
Gene:
FAP
Gene ID:
2191
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ24 |
|---|---|
| Product Name | FAP Knockout U-87 MG Cell Line |
| Cell Line | U-87MG ATCC |
| Cellosaurus ID | CVCL_0022 |
| Cell Line Synonyms | U-87MG, U-87 MG, U87 MG, U-87-MG, U87-MG, U87MG, U-87, U87, 87 MG, 87MG |
| Gene | FAP |
| Gene Synonyms | DPPIV|FAPA|FAPalpha|SIMP |
| Summary |
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
|
| Associated Diseases | Glioblastoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: U-87MG ATCC | STR Info (Cell bank) Cell Line: U-87MG ATCC | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 11 | 10 | 11 |
| D2S1338 | 20 | 23 | 20 | 23 |
| D3S1358 | 16 | 17 | 16 | 17 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 8 | 9 | 8 | 9 |
| D8S1179 | 10 | 11 | 10 | 11 |
| D13S317 | 8 | 11 | 8 | 11 |
| D16S539 | 12 | 12 | ||
| D18S51 | 13 | 13 | ||
| D19S433 | 15 | 15.2 | 15 | 15.2 |
| D21S11 | 28 | 32.2 | 28 | 32.2 |
| FGA | 18 | 24 | 18 | 24 |
| Penta D | 9 | 14 | 9 | 14 |
| Penta E | 7 | 14 | 7 | 14 |
| TH01 | 9.3 | 9.3 | ||
| TPOX | 8 | 8 | ||
| vWA | 15 | 17 | 15 | 17 |
| D6S1043 | 11 | 18 | ||
| D12S391 | 18 | 21 | 18 | 21 |
| D2S441 | 10 | 11 | 10 | 11 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.