DSC2 Knockout MGC-803 Cell Line
Cat.No.:
EDJ-KZ193
Species:
Human
Cell Name:
MGC-803
Gene:
DSC2
Gene ID:
1824
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ193 |
|---|---|
| Product Name | DSC2 Knockout MGC80-3 Cell Line |
| Species | Human |
| Cell Line | MGC-803 |
| Cellosaurus ID | CVCL_5334 |
| Cell Line Synonyms | MGC803, MGc80-3 |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | ARVD11|CDHF2|DG2|DGII/III|DSC3 |
| Summary |
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
|
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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