Cbs Knockout HT22 Cell Line
Cat.No.:
EDJ-KZ132
Species:
Mouse
Cell Name:
HT22
Gene:
Cbs
Gene ID:
12411
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ132 |
|---|---|
| Product Name | Cbs Knockout HT22 Cell Line |
| Cell Line | HT22 |
| Cellosaurus ID | CVCL_0321 |
| Gene | Cbs |
| NCBI Gene ID | |
| Gene Synonyms | CBSL|HIP4 |
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: HT22 | STR Info (Cell bank) Cell Line: HT22 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| 1-1 | 10 | 11 | 10 | 11 | ||
| 1-2 | 13 | 17 | 13 | 17 | ||
| 2-1 | 9 | 9 | ||||
| 3-2 | 14 | 15 | 14 | 15 | ||
| 4-2 | 18.3 | 19.3 | 20.3 | 18.3 | 19.3 | 20.3 |
| 5-5 | 13 | 14 | 15 | 13 | 14 | 15 |
| 6-4 | 16 | 15.3 | ||||
| 6-7 | 12 | 12 | ||||
| 7-1 | 29 | 29 | ||||
| 8-1 | 15 | 15 | ||||
| 11-2 | 15 | 17 | 18 | 15 | 17 | 18 |
| 12-1 | 20 | 20 | ||||
| 13-1 | 16.2 | 16.2 | ||||
| 15-3 | 20.3 | 20.3 | ||||
| 17-2 | 12 | 13 | 14 | 12 | 13 | 14 |
| 18-3 | 17 | 19 | 17 | 19 | ||
| 19-2 | 11 | 12 | 11 | 12 | ||
| X-1 | 25 | 25 | ||||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Related Publications
Vitamin B alleviates chronic sleep deprivation-induced hippocampal ferroptosis through CBS/GSH/GPX4 pathway.
IF=7.5
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
This KO model may be useful for:
- Investigating the role of CBS in ferroptosis regulation via the GSH/GPX4 pathway
- Studying molecular mechanisms underlying chronic sleep deprivation-induced neurodegeneration
- Screening neuroprotective agents targeting CBS-mediated oxidative stress and iron metabolism
- Evaluating vitamin B or other nutrient-based interventions in ferroptosis-related disease models
- Functional validation of CBS in hippocampal cell survival and redox homeostasis
Required Accessories
Cell Culture Optimization Series
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