CACNA1D Knockout Caco-2 Cell Line
Cat.No.:
EDJ-KQ12
Species:
Human
Cell Name:
Caco-2
Gene:
CACNA1D
Gene ID:
776
Size:
1×10⁶cells
Cav1.3 Knockout Cell Line (CaCO-2) is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performotion Cas9 Protein and Hassle-Free Cell Selection.
| Cat.No. | EDJ-KQ12 |
|---|---|
| Product Name | Cav1.3 Knockout Cell Line (CaCO-2) |
| Cell line | CaCO-2 |
| Cellosaurus ID | CVCL_0025 |
| Cell Line Synonyms | CaCo-2, CACO-2, Caco 2, CACO 2, CACO2, CaCo2, CaCO2, Caco2, Caco-2/ATCC, Caco-II |
| Gene | CACNA1D |
| NCBI Gene ID | |
| Summary |
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
|
| Morphology | Adherent |
| Passage Ratio | 1/4，2~3days |
| Complete Culture Medium | DMEM + 10% FBS；MEM+NEAA+20% FBS（procell） |
| Freezing Medium | 70% Complete culture medium + 20% FBS+ 10% DMSO |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: Caco-2 | STR Info (Cell bank) Cell Line: Caco-2 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| Amelogenin | X | X | ||||
| CSF1PO | 11 | 11 | ||||
| D5S818 | 12 | 13 | 12 | 13 | ||
| D7S820 | 11 | 12 | 11 | 12 | ||
| D13S317 | 11 | 13 | 14 | 11 | 13 | 14 |
| D16S539 | 12 | 13 | 12 | 13 | ||
| TPOX | 9 | 11 | 9 | 11 | ||
| vWA | 16 | 18 | 16 | 18 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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