CYP4F12 Knockout A-549 Cell Line

CYP4F12 Knockout A-549 Cell Line
Cat.No.:

EDJ-KQ42354

Species:

Human

Cell Name:

A-549

Gene:

CYP4F12

Gene ID:

66002

Size:

1×10⁶cells

CYP4F12 Knockout Cell Line (A549) is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performance Cas9 Protein and Hassle-Free Cell Selection.
Cat.No. EDJ-KQ42354
Product Name CYP4F12 Knockout A549 Cell Line
Cell Line A-549
Cellosaurus ID CVCL_0023
Cell Line Synonyms A 549, A549, NCI-A549, A549/ATCC, A549 ATCC, A549ATCC, hA549
Gene
NCBI Gene ID
Gene Synonyms CYPIVF12|F22329_1
Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Associated Diseases Non-Small Cell Lung Carcinoma
Morphology Adherent
Passage Ratio 1/5-1/4 ,2days
Complete Culture Medium F-12K + 10% FBS
Freezing Medium 95% Complete culture medium + 5% DMSO
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: A-549
STR Info (Cell bank)
Cell Line: A-549
Allele1Allele2Allele1Allele2
Amelogenin X Y X Y
CSF1PO 10 12 10 12
D2S1338 24 24
D3S1358 16 16
D5S818 11 11
D7S820 8 11 8 11
D8S1179 13 14 13 14
D13S317 11 11
D16S539 11 12 11 12
D18S51 14 17 14 17
D19S433 13 13
D21S11 29 29
FGA 23 23
Penta D 9 9
Penta E 7 11 7 11
TH01 8 9.3 8 9.3
TPOX 8 11 8 11
vWA 14 14
D6S1043 11 13
D12S391 18 18
D2S441 10 13 10 13
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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