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CAV2 Knockout PANC-1 Cell Line
Cat.No.:
EDJ-KZ131
Species:
Human
Cell Name:
PANC-1
Gene:
CAV2
Gene ID:
858
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ131 |
|---|---|
| Product Name | CAV2 Knockout panc-1 Cell Line |
| Cell Line | panc-1 |
| Cellosaurus ID | CVCL_0480 |
| Cell Line Synonyms | Panc-1, PANC.1, Panc 1, PanC1, Panc1, PANC1, Panc-1-P |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | CAV |
| Summary |
The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]
|
| Associated Diseases | Pancreatic Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: PANC-1 | STR Info (Cell bank) Cell Line: PANC-1 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 12 | 10 | 12 |
| D5S818 | 11 | 13 | 11 | 13 |
| D7S820 | 8 | 10 | 8 | 10 |
| D13S317 | 11 | 11 | ||
| D16S539 | 11 | 11 | ||
| TPOX | 8 | 11 | 8 | 11 |
| vWA | 15 | 15 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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