pU6-CYP2C9-pegRNA-sgRNA-Puro
EDITGENE guarantees pU6-CYP2C9-pegRNA-sgRNA-Puro has passed QC, endotoxin-free, and project validated. more
Cat.No: EDV438
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EDITGENE guarantees pU6-CYP2C9-pegRNA-sgRNA-Puro has passed QC, endotoxin-free, and project validated.
| Plasmid Resistance | Amp |
|---|---|
| Type | PE |
| Selection Marker | Puro |
| Gene ID | |
| Gene | CYP2C9 |
| Gene Synonyms | CPC9|CYP2C|CYP2C10|CYPIIC9|P450-2C9|P450IIC9 |
| Summary |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
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* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
Storage
Store at -20 ºC for short term. -80 ºC for long term preservation.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
