MSLN Overexpression K-562 Stable Cell Line
Cat.No.:
EDC01466
Species:
Human
Cell Name:
K-562
Gene:
MSLN
Gene ID:
10232
Size:
1×10⁶cells
EDITGENE's MSLN Overexpression K-562 Stable Cell Line is a QC-validated, mycoplasma-free overexpression stable cell line, providing reliable long-term gene expression for functional studies and biopharmaceutical research.
| Product Name | MSLN Overexpression K-562 Stable Cell Line |
|---|---|
| Cellosaurus ID | CVCL_U226 |
| Cell Line Synonyms | K562, K.562, K 562, KO, GM05372, GM05372E |
| Gene | MSLN |
| Gene Synonyms | MPF|SMRP |
| Summary |
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
|
| Associated Diseases | Chronic Myelogenous Leukemia |
| Morphology | Lymphoblastoid, suspended growth |
| Complete Culture Medium | 1640+10%FBS |
| Freezing Medium | 95%Complete culture medium+5%DMSO |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: K-562 | STR Info (Cell bank) Cell Line: K-562 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1P0 | 9 | 10 | 9 | 10 |
| D2S1338 | 17 | 17 | ||
| D3S1358 | 16 | 16 | ||
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 9 | 11 | 9 | 11 |
| D8S1179 | 12 | 12 | ||
| D13S317 | 8 | 8 | ||
| D16S539 | 11 | 12 | 11 | 12 |
| D18S51 | 15 | 16 | 15 | 16 |
| D19S433 | 14 | 14.2 | 14 | 14.2 |
| D21S11 | 29 | 31 | 29 | 31 |
| FGA | 21 | 24 | 21 | 24 |
| Penta D | 9 | 13 | 9 | 13 |
| Penta E | 5 | 14 | 5 | 14 |
| TH01 | 9.3 | 9.3 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 16 | 16 | ||
| D6S1043 | 11 | |||
| D12S391 | 23 | 23 | ||
| D2S441 | 10 | 14 | 10 | 14 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
