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LRP1 Overexpression Jurkat E6.1 Stable Cell Line
Cat.No.:
EDC01588
Species:
Human
Cell Name:
Jurkat E6.1
Gene:
LRP1
Gene ID:
4035
Size:
1×10⁶cells
EDITGENE's LRP1 Overexpression Jurkat E6.1 Stable Cell Line is a QC-validated, mycoplasma-free overexpression stable cell line, providing reliable long-term gene expression for functional studies and biopharmaceutical research.
| Cat.No. | EDC01588 |
|---|---|
| Product Name | LRP1 Overexpression Jurkat E6.1 Stable Cell Line |
| Cell Line | Jurkat E6.1 |
| Gene ID | |
| Gene | |
| Summary |
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]
|
| Morphology | Suspension |
| Passage Ratio | / |
| Complete Culture Medium | RPMI-1640 + 10% FBS |
| Freezing Medium | 95% Complete medium + 5% DMSO |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: Jurkat E6.1 | STR Info (Cell bank) Cell Line: Jurkat E6.1 | ||||||
| Allele1 | Allele2 | Allele3 | Allele4 | Allele1 | Allele2 | Allele3 | Allele4 | |
| Amelogenin | X | Y | X | Y | ||||
| CSF1PO | 10 | 11 | 12 | 13 | 10 | 11 | 12 | 13 |
| CSF1PO | 11 | 12 | 11 | 12 | ||||
| D2S1338 | 19 | 23 | 19 | 23 | ||||
| D3S1358 | 15 | 15 | ||||||
| D3S1358 | 15 | 17 | 15 | 17 | ||||
| D5S818 | 9 | 9 | ||||||
| D7S820 | 8 | 10 | 8 | 10 | ||||
| D7S820 | 8 | 12 | 8 | 12 | ||||
| D8S1179 | 12 | 13 | 14 | 15 | 12 | 13 | 14 | 15 |
| D8S1179 | 13 | 14 | 13 | 14 | ||||
| D13S317 | 8 | 12 | 8 | 12 | ||||
| D16S539 | 11 | 11 | ||||||
| D18S51 | 12 | 13 | 20 | 21 | 12 | 13 | 20 | 21 |
| D18S51 | 13 | 21 | 13 | 21 | ||||
| D19S433 | 14 | 15.2 | 14 | 15.2 | ||||
| D21S11 | 30.2 | 31.2 | 33.2 | 30.2 | 31.2 | 33.2 | ||
| D21S11 | 31.2 | 33.2 | 31.2 | 33.2 | ||||
| FGA | 20 | 21 | 20 | 21 | ||||
| Penta D | 11 | 13 | 11 | 13 | ||||
| Penta E | 10 | 12 | 10 | 12 | ||||
| TH01 | 6 | 9.3 | 6 | 9.3 | ||||
| TPOX | 8 | 10 | 8 | 10 | ||||
| vWA | 18 | 18 | ||||||
| vWA | 18 | 19 | 18 | 19 | ||||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
