Product Details
| Cat.No. | EDC01304 | Product Name | HT-22-Cas9 |
|---|---|---|---|
| Species | Mouse | Cell Line | HT22 |
| Cellosaurus ID | CVCL_0321 | Cell Line Synonyms | HT-22 |
| Gene Synonyms | CD49e|FNRA|VLA-5|VLA5A | Summary |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
|
| Associated Diseases | Non-tumor | Morphology | Adherent |
| Editing Efficiency | 83% | Complete Culture Medium | 90% FBS+10% DMSO |
| Freezing Medium | DMEM+10% FBS |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
STR Profile
| Loci | STR Info (Sample Cell) Sample Cell Line: HT22 | STR Info (Cell bank) Cell Line: HT22 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| 1-1 | 10 | 11 | 10 | 11 | ||
| 1-2 | 13 | 17 | 13 | 17 | ||
| 2-1 | 9 | 9 | ||||
| 3-2 | 14 | 15 | 14 | 15 | ||
| 4-2 | 18.3 | 19.3 | 20.3 | 18.3 | 19.3 | 20.3 |
| 5-5 | 13 | 14 | 15 | 13 | 14 | 15 |
| 6-4 | 16 | 15.3 | ||||
| 6-7 | 12 | 12 | ||||
| 7-1 | 29 | 29 | ||||
| 8-1 | 15 | 15 | ||||
| 11-2 | 15 | 17 | 18 | 15 | 17 | 18 |
| 12-1 | 20 | 20 | ||||
| 13-1 | 16.2 | 16.2 | ||||
| 15-3 | 20.3 | 20.3 | ||||
| 17-2 | 12 | 13 | 14 | 12 | 13 | 14 |
| 18-3 | 17 | 19 | 17 | 19 | ||
| 19-2 | 11 | 12 | 11 | 12 | ||
| X-1 | 25 | 25 | ||||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
