GLA (p.D155E) Point Mutation in AC16 Cell Line
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Cat.No.:
EDC03189
Cell Name:
AC16 [Human hybrid cardiomyocyte]
Gene:
GLA
Gene ID:
2717
Size:
1×10⁶cells
The GLA (p.D155E) Point Mutation in AC16 Cell Line is based on the newly developed Bingo™ platform, which utilizes an optimized and upgraded version of the Prime Editing (PE) gene point mutation system-currently the most efficient and safest technology available. This platform enables precise and efficient gene point mutation, resulting in a highly active and stable cell line.
| Cat.No. | EDC03189 |
|---|---|
| Product Name | GLA (p.D155E) Point Mutation in AC16 Cell Line |
| Gene ID | |
| Mutation Site | p.D155E |
| Cellosaurus ID | CVCL_4U18 |
| Summary |
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Non-tumor |
| Passage Ratio | 1:3 |
| Complete Culture Medium | DMEM+10%FBS |
| Freezing Medium | 95% complete culture medium+5% DMSO |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: AC16 [Human hybrid cardiomyocyte] | STR Info (Cell bank) Cell Line: AC16 [Human hybrid cardiomyocyte] | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| Amelogenin | X | X | ||||
| CSF1PO | 9 | 11 | 12 | 9 | 11 | 12 |
| D2S1338 | 20 | 23 | 26 | |||
| D3S1358 | 17 | 18 | 17 | 18 | ||
| D5S818 | 9 | 11 | 9 | 11 | ||
| D7S820 | 10 | 11 | 12 | 10 | 11 | 12 |
| D8S1179 | 14 | 15 | 12 | 14 | ||
| D13S317 | 12 | 13 | 12 | 13 | ||
| D16S539 | 11 | 13 | 11 | 13 | ||
| D18S51 | 12 | 17 | 12 | 17 | ||
| D19S433 | 15 | 15.2 | ||||
| D21S11 | 32.2 | 32.2 | 33.2 | |||
| FGA | 21 | 25 | 21 | 25 | ||
| Penta D | 2.2 | 9 | 2.2 | 9 | ||
| Penta E | 7 | 12 | 16 | 7 | 8 | 16 |
| TH01 | 7 | 8 | 9.3 | 7 | 8 | 9.3 |
| TPOX | 11 | 11 | ||||
| vWA | 16 | 18 | 16 | 18 | ||
| D6S1043 | 14 | 17 | ||||
| D12S391 | 17.3 | 18 | 21 | |||
| D2S441 | 10 | 14 | ||||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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