4T1-Cas9
Cat.No.:
EDC01265
Species:
Mouse
Cell Name:
4T1
Size:
1×10⁶cells
4T1-Cas9 Cell Line meets our QC standard. Low passage, high activity, contamination free. Useful for various vitro studies.
| Cat.No. | EDC01265 |
|---|---|
| Product Name | 4T1-Cas9 |
| Species | Mouse |
| Cell Line | 4T1 |
| Cellosaurus ID | CVCL_0125 |
| Cell Line Synonyms | 4T1-A, 4T1.0, 4T1/WT |
| Gene Synonyms | CTHBP|HEL-S-30|OIP3|PK3|PKM2|TCB|THBP1|p58 |
| Summary |
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
|
| Associated Diseases | Breast cancer |
| Morphology | Adherent |
| Editing Efficiency | 96% |
| Complete Culture Medium | 95% complete culture medium+5% DMSO |
| Freezing Medium | 1640+10% FBS |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: 4T1 | STR Info (Cell bank) Cell Line: 4T1 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| 1-1 | 16 | 15 | 16 | |||
| 1-2 | 17 | 17 | ||||
| 2-1 | 16 | 17 | 16 | 17 | ||
| 3-2 | 14 | 15 | 14 | 15 | ||
| 4-2 | 21.3 | 21.3 | ||||
| 5-5 | 14 | 14 | ||||
| 6-4 | 18 | 18 | ||||
| 6-7 | 12 | 12 | ||||
| 7-1 | 25.2 | 25.2 | ||||
| 8-1 | 13 | 13 | ||||
| 11-2 | 18 | 19 | 18 | 19 | 20 | |
| 12-1 | 16 | 17 | 16 | |||
| 13-1 | 16.2 | 16.2 | ||||
| 15-3 | 22.3 | 22.3 | ||||
| 17-2 | 15 | 15 | ||||
| 18-3 | 18 | 19 | 18 | 19 | ||
| 19-2 | 13 | 13 | ||||
| X-1 | 24 | 25 | 25 | |||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
