XKR9: XK-Related Protein 9
A member of the XK family of putative potassium transport proteins, with limited functional characterization.
Gene Information Card
| Symbol | XKR9 |
|---|---|
| Full Name | XK-related protein 9 |
| Gene Type | protein-coding |
| Chromosomal Location | 8q13.3 |
| NCBI Gene ID | 101928376 ncbi.nlm.nih.gov/gene/101928376 |
| Ensembl ID | ENSG00000205571 |
| UniProt ID | A6NNA5 |
| OMIM ID | - |
| HGNC ID | 33793 |
| Aliases | XK-related 9, XK, Kell blood group complex subunit-related family member 9 |
Description
XKR9 (XK-related protein 9) is a protein-coding gene belonging to the XK family, which is involved in potassium transport and membrane integrity. The gene is located on chromosome 8q13.3 and encodes a predicted multi-pass membrane protein. Its specific biological function remains largely uncharacterized, but it is thought to participate in cation transport and may be implicated in red blood cell membrane biology.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| - | - | No disease associations currently documented in OMIM, ClinVar, or COSMIC. |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| - | - | No tissue expression data available from GTEx or Human Protein Atlas for XKR9. |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| - | - | No cell line expression data available. |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| - | - | No mutations reported in COSMIC or ClinVar. |
Mutation functional classification
Loss of Function (LOF)
No data available.
Gain of Function (GOF)
No data available.
Dominant Negative (DN)
No data available.
View complete mutation data：
Protein Summary
XKR9 is a predicted multi-pass membrane protein of unknown function. It belongs to the XK family, which includes proteins involved in potassium transport and red blood cell membrane integrity. No experimental characterization of the protein has been reported.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| XKR9 Knockout HEK293 Cell Line | EDJ-KQ16160 | Human | 389668 | Details Get a Quote |
| XKR9 Knockout A-549 Cell Line | EDJ-KQ47350 | Human | 389668 | Details Get a Quote |
| XKR9 Knockout HeLa Cell Line | EDJ-KQ60097 | Human | 389668 | Details Get a Quote |
| XKR9 Knockout HCT 116 Cell Line | EDJ-KQ76935 | Human | 389668 | Details Get a Quote |
