TMEM178B
Transmembrane Protein 178B
Gene Information Card
| Symbol | TMEM178B |
|---|---|
| Full Name | Transmembrane Protein 178B |
| Gene Type | protein-coding |
| Chromosomal Location | 7p21.3 |
| NCBI Gene ID | 100507246 ncbi.nlm.nih.gov/gene/100507246 |
| Ensembl ID | ENSG00000205562 |
| UniProt ID | A6NMS5 |
| OMIM ID | - |
| HGNC ID | 37238 |
| Aliases | MGC16384, FLJ46321 |
Description
TMEM178B (Transmembrane Protein 178B) is a protein-coding gene located on chromosome 7p21.3. It encodes a transmembrane protein with unknown function. Limited expression data suggest low to moderate expression in certain tissues. No disease associations have been firmly established.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No confirmed disease associations | - | - |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.8 | Low |
| Brain | 0.5 | Low |
| Lung | 0.3 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 0.6 | Low expression |
| K562 | 0.4 | Low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported pathogenic variants | - | - | - |
Mutation functional classification
Loss of Function (LOF)
No data
Gain of Function (GOF)
No data
Dominant Negative (DN)
No data
View complete mutation data：
Protein Summary
TMEM178B is a transmembrane protein of unknown function. It is predicted to be localized to the membrane. No functional domains or motifs have been characterized.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| TMEM178B Knockout HEK293 Cell Line | EDJ-KQ12026 | Human | 100507421 | Details Get a Quote |
| TMEM178B Knockout HeLa Cell Line | EDJ-KQ60924 | Human | 100507421 | Details Get a Quote |
| TMEM178B Knockout A-549 Cell Line | EDJ-KQ69399 | Human | 100507421 | Details Get a Quote |
| TMEM178B Knockout HCT 116 Cell Line | EDJ-KQ77751 | Human | 100507421 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
