TAF11L8 Gene - TATA-Box Binding Protein Associated Factor 11 Like 8
A comprehensive biomedical overview of TAF11L8, including genomic context, expression, and functional annotations.
Gene Information Card
| Symbol | TAF11L8 |
|---|---|
| Full Name | TATA-box binding protein associated factor 11 like 8 |
| Gene Type | protein-coding |
| Chromosomal Location | 5q35.3 |
| NCBI Gene ID | 100129923 ncbi.nlm.nih.gov/gene/100129923 |
| Ensembl ID | ENSG00000234015 |
| UniProt ID | A0A0A0MRZ2 |
| OMIM ID | None |
| HGNC ID | HGNC:44277 |
| Aliases | TAF11-like 8, TAF11L8 |
Description
TAF11L8 is a protein-coding gene located on chromosome 5q35.3. It is predicted to encode a protein similar to TAF11, a subunit of the transcription factor IID (TFIID) complex. The gene is part of a family of TAF11-like genes, but its specific biological function remains largely uncharacterized. According to NCBI, it is a novel gene with limited experimental evidence.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease association | Not established | No curated disease links in OMIM or ClinVar |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.0 | Not detected |
| Brain | 0.0 | Not detected |
| Liver | 0.0 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HeLa | 0.0 | Not detected |
| K562 | 0.0 | Not detected |
| MCF7 | 0.0 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported variants | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The TAF11L8 protein is predicted to be 211 amino acids long and may contain a TAF11-like domain. However, no experimental evidence exists for its function, subcellular localization, or interactions. It is likely a non-functional pseudogene or a protein with a highly restricted expression pattern, as RNA-seq data from major tissues and cell lines show no expression.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| TAF11L8 Knockout HEK293 Cell Line | EDJ-KQ15599 | Human | 112488737 | Details Get a Quote |
| TAF11L8 Knockout A-549 Cell Line | EDJ-KQ46479 | Human | 112488737 | Details Get a Quote |
| TAF11L8 Knockout HCT 116 Cell Line | EDJ-KQ46480 | Human | 112488737 | Details Get a Quote |
| TAF11L8 Knockout HeLa Cell Line | EDJ-KQ46481 | Human | 112488737 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
