SYCE1L
Synaptonemal Complex Central Element Protein 1 Like
Gene Information Card
| Symbol | SYCE1L |
|---|---|
| Full Name | Synaptonemal Complex Central Element Protein 1 Like |
| Gene Type | protein-coding |
| Chromosomal Location | 16p13.3 |
| NCBI Gene ID | 100130275 ncbi.nlm.nih.gov/gene/100130275 |
| Ensembl ID | ENSG00000204310 |
| UniProt ID | A6NKD9 |
| OMIM ID | 618409 |
| HGNC ID | 37278 |
| Aliases | SYCE1-like, C16orf91 |
Description
SYCE1L encodes a protein similar to SYCE1, a component of the synaptonemal complex central element essential for homologous chromosome pairing and recombination during meiosis. The specific function of SYCE1L is not fully characterized but is predicted to play a role in meiotic chromosome synapsis.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations currently curated | Not applicable | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.0 | Not detected |
| Ovary | 0.0 | Not detected |
| All other tissues | 0.0 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| No data available | N/A | N/A |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No pathogenic variants reported | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
SYCE1L is a 244-amino acid protein with no experimentally determined structure. It shares sequence similarity with SYCE1, a central element protein of the synaptonemal complex. Its biological role remains to be elucidated.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| SYCE1L Knockout HEK293 Cell Line | EDJ-KQ15577 | Human | 100130958 | Details Get a Quote |
| SYCE1L Knockout HCT 116 Cell Line | EDJ-KQ45217 | Human | 100130958 | Details Get a Quote |
| SYCE1L Knockout A-549 Cell Line | EDJ-KQ46444 | Human | 100130958 | Details Get a Quote |
| SYCE1L Knockout HeLa Cell Line | EDJ-KQ46446 | Human | 100130958 | Details Get a Quote |
