SPATA31A6
SPATA31 Subfamily A Member 6
Gene Information Card
| Symbol | SPATA31A6 |
|---|---|
| Full Name | SPATA31 Subfamily A Member 6 |
| Gene Type | protein-coding |
| Chromosomal Location | 9q34.3 |
| NCBI Gene ID | 127294 ncbi.nlm.nih.gov/gene/127294 |
| Ensembl ID | ENSG00000180592 |
| UniProt ID | Q5VY43 |
| OMIM ID | - |
| HGNC ID | 33848 |
| Aliases | SPATA31A6, FAM75A6 |
Description
SPATA31A6 is a protein-coding gene belonging to the SPATA31 (spermatogenesis associated 31) subfamily A. The gene is located on chromosome 9q34.3 and encodes a protein of unknown function. It is primarily expressed in testis and is thought to be involved in spermatogenesis, though detailed functional studies are limited.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No curated disease associations | - | - |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.3 | Low |
| Other tissues | <0.1 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| No cell line data available | - | - |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations in COSMIC or ClinVar | - | - | - |
Mutation functional classification
Loss of Function (LOF)
Not established
Gain of Function (GOF)
Not established
Dominant Negative (DN)
Not established
View complete mutation data：
Protein Summary
The SPATA31A6 protein (UniProt Q5VY43) is 1,063 amino acids long with no characterized domains or known function. It is predicted to be involved in spermatogenesis based on gene family membership, but experimental evidence is lacking.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| SPATA31A6 Knockout HEK293 Cell Line | EDJ-KQ15446 | Human | 389730 | Details Get a Quote |
| SPATA31A6 Knockout HeLa Cell Line | EDJ-KQ60100 | Human | 389730 | Details Get a Quote |
| SPATA31A6 Knockout A-549 Cell Line | EDJ-KQ68562 | Human | 389730 | Details Get a Quote |
| SPATA31A6 Knockout HCT 116 Cell Line | EDJ-KQ76938 | Human | 389730 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
