RMC1
Regulator of Monocyte to Macrophage Differentiation 1
Gene Information Card
| Symbol | RMC1 |
|---|---|
| Full Name | regulator of monocyte to macrophage differentiation 1 |
| Gene Type | protein-coding |
| Chromosomal Location | 18q21.1 |
| NCBI Gene ID | 100131801 ncbi.nlm.nih.gov/gene/100131801 |
| Ensembl ID | ENSG00000267280 |
| UniProt ID | A0A1B0GTV5 |
| OMIM ID | 618824 |
| HGNC ID | HGNC:33738 |
| Aliases | MGC16121, dJ1181N3.1 |
Description
RMC1 (regulator of monocyte to macrophage differentiation 1) is a protein-coding gene located on chromosome 18q21.1. It is involved in the regulation of monocyte differentiation into macrophages. The gene encodes a protein that may play a role in immune cell development and function.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations currently curated | Not established | No evidence in ClinVar, OMIM, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| No tissue expression data available | N/A | N/A |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| No cell line expression data available | N/A | N/A |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No mutations currently curated | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
Not established
Gain of Function (GOF)
Not established
Dominant Negative (DN)
Not established
View complete mutation data：
Protein Summary
The RMC1 protein is predicted to be involved in monocyte to macrophage differentiation. Its exact molecular function and structure are not fully characterized. UniProt entry A0A1B0GTV5 provides a predicted sequence but limited functional annotation.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| PGRMC1 Knockout HEK293 Cell Line | EDJ-KQ7190 | Human | 10857 | Details Get a Quote |
| ARMC12 Knockout HEK293 Cell Line | EDJ-KQ8833 | Human | 221481 | Details Get a Quote |
| ARMC10 Knockout HEK293 Cell Line | EDJ-KQ9903 | Human | 83787 | Details Get a Quote |
| ARMC1 Knockout HEK293 Cell Line | EDJ-KQ12432 | Human | 55156 | Details Get a Quote |
| RMC1 Knockout HEK293 Cell Line | EDJ-KQ15084 | Human | 29919 | Details Get a Quote |
| RMC1 Knockout HeLa Cell Line | EDJ-KQ17929 | Human | 29919 | Details Get a Quote |
| PGRMC1 Knockout A-549 Cell Line | EDJ-KQ32130 | Human | 10857 | Details Get a Quote |
| PGRMC1 Knockout HCT 116 Cell Line | EDJ-KQ32131 | Human | 10857 | Details Get a Quote |
| PGRMC1 Knockout HeLa Cell Line | EDJ-KQ32132 | Human | 10857 | Details Get a Quote |
| ARMC1 Knockout A-549 Cell Line | EDJ-KQ41354 | Human | 55156 | Details Get a Quote |
| ARMC1 Knockout HCT 116 Cell Line | EDJ-KQ41355 | Human | 55156 | Details Get a Quote |
| ARMC1 Knockout HeLa Cell Line | EDJ-KQ41356 | Human | 55156 | Details Get a Quote |
| ARMC10 Knockout A-549 Cell Line | EDJ-KQ36792 | Human | 83787 | Details Get a Quote |
| ARMC10 Knockout HCT 116 Cell Line | EDJ-KQ36793 | Human | 83787 | Details Get a Quote |
| ARMC10 Knockout HeLa Cell Line | EDJ-KQ36794 | Human | 83787 | Details Get a Quote |
Displaying Records 1 To 15 Of 20 Records
