NAT16: N-Acetyltransferase 16 (Putative)
A member of the N-acetyltransferase family with limited functional characterization
Gene Information Card
| Symbol | NAT16 |
|---|---|
| Full Name | N-Acetyltransferase 16 (Putative) |
| Gene Type | Protein coding |
| Chromosomal Location | 7q36.1 |
| NCBI Gene ID | 123879 ncbi.nlm.nih.gov/gene/123879 |
| Ensembl ID | ENSG00000185619 |
| UniProt ID | Q6N028 |
| OMIM ID | Not assigned |
| HGNC ID | 29812 |
| Aliases | MGC13170, FLJ32871 |
Description
NAT16 (N-Acetyltransferase 16) is a protein-coding gene located on chromosome 7q36.1. It belongs to the N-acetyltransferase family, which catalyzes the transfer of acetyl groups from acetyl-CoA to various substrates. The function of NAT16 is not fully characterized, but it is predicted to be involved in acetylation processes. Expression data suggest broad but low-level tissue distribution.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No confirmed disease associations | Not established | No curated evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 2.3 | Low |
| Thyroid | 1.8 | Low |
| Adrenal gland | 1.5 | Low |
| Brain | 1.2 | Low |
| Liver | 1.0 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK 293 | 1.5 | Low expression |
| K-562 | 1.2 | Low expression |
| HeLa | 1.0 | Low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated variants | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
Not characterized
Gain of Function (GOF)
Not characterized
Dominant Negative (DN)
Not characterized
View complete mutation data：
Gene Ontology (GO)
| • N-acetyltransferase activity (GO:0008080) | • cytoplasm (GO:0005737) |
Protein Summary
The NAT16 protein (UniProt Q6N028) is a putative N-acetyltransferase of 207 amino acids. Its molecular function is predicted to involve acetyltransferase activity, but specific substrates and biological roles remain unknown. No crystal structure is available.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| NAT16 Knockout HEK293 Cell Line | EDJ-KQ14377 | Human | 375607 | Details Get a Quote |
| NAT16 Knockout HeLa Cell Line | EDJ-KQ59928 | Human | 375607 | Details Get a Quote |
| NAT16 Knockout A-549 Cell Line | EDJ-KQ68389 | Human | 375607 | Details Get a Quote |
| NAT16 Knockout HCT 116 Cell Line | EDJ-KQ76769 | Human | 375607 | Details Get a Quote |
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