MT1HL1
Metallothionein 1H Like 1
Gene Information Card
| Symbol | MT1HL1 |
|---|---|
| Full Name | Metallothionein 1H Like 1 |
| Gene Type | protein-coding |
| Chromosomal Location | 16q13 |
| NCBI Gene ID | 100131359 ncbi.nlm.nih.gov/gene/100131359 |
| Ensembl ID | ENSG00000204388 |
| UniProt ID | Q8N7Z2 |
| OMIM ID | N/A |
| HGNC ID | HGNC:33607 |
| Aliases | MT1HL1 |
Description
MT1HL1 (Metallothionein 1H Like 1) is a protein-coding gene located on chromosome 16q13. It belongs to the metallothionein family of proteins that bind heavy metals and are involved in metal homeostasis and detoxification. The gene is primarily expressed in testis and has limited characterized function.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No known disease associations | Not established | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.5 | Low |
| Other tissues | Not detected | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| No data available | N/A | No expression data in cell lines from GTEx or related sources |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported mutations | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
Not characterized
Gain of Function (GOF)
Not characterized
Dominant Negative (DN)
Not characterized
View complete mutation data：
Protein Summary
The MT1HL1 protein is predicted to be a small, cysteine-rich metallothionein-like protein. Its exact function is unknown, but it may participate in metal ion binding and cellular stress responses based on sequence homology.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| MT1HL1 Knockout HEK293 Cell Line | EDJ-KQ14325 | Human | 645745 | Details Get a Quote |
| MT1HL1 Knockout HeLa Cell Line | EDJ-KQ60590 | Human | 645745 | Details Get a Quote |
| MT1HL1 Knockout A-549 Cell Line | EDJ-KQ69060 | Human | 645745 | Details Get a Quote |
| MT1HL1 Knockout HCT 116 Cell Line | EDJ-KQ77414 | Human | 645745 | Details Get a Quote |
