LRRC73
Leucine Rich Repeat Containing 73
Gene Information Card
| Symbol | LRRC73 |
|---|---|
| Full Name | Leucine Rich Repeat Containing 73 |
| Gene Type | protein-coding |
| Chromosomal Location | 6p21.1 |
| NCBI Gene ID | 100131801 ncbi.nlm.nih.gov/gene/100131801 |
| Ensembl ID | ENSG00000204371 |
| UniProt ID | Q5VY43 |
| OMIM ID | - |
| HGNC ID | 34347 |
| Aliases | MGC16384, dJ104K21.2 |
Description
LRRC73 (Leucine Rich Repeat Containing 73) is a protein-coding gene located on chromosome 6p21.1. The encoded protein contains leucine-rich repeats, which are typically involved in protein-protein interactions. The function of LRRC73 is not fully characterized, but it is predicted to play a role in cellular signaling or immune response based on its domain architecture.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No specific disease associations | Not established | No evidence from ClinVar, OMIM, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.8 | Low |
| Lymph node | 0.5 | Low |
| Spleen | 0.4 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK 293 | 0.3 | Low expression |
| K562 | 0.2 | Low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations | - | - | - |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Gene Ontology (GO)
| • protein binding (GO:0005515) |
Protein Summary
The LRRC73 protein (UniProt Q5VY43) is 276 amino acids long and contains leucine-rich repeats. Its exact biological function remains unknown, but it is predicted to be involved in protein-protein interactions. No structural or functional studies have been published.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| LRRC73 Knockout HEK293 Cell Line | EDJ-KQ8823 | Human | 221424 | Details Get a Quote |
| LRRC73 Knockout HeLa Cell Line | EDJ-KQ59168 | Human | 221424 | Details Get a Quote |
| LRRC73 Knockout A-549 Cell Line | EDJ-KQ67641 | Human | 221424 | Details Get a Quote |
| LRRC73 Knockout HCT 116 Cell Line | EDJ-KQ76026 | Human | 221424 | Details Get a Quote |
