LRRC10B
Leucine Rich Repeat Containing 10B
Gene Information Card
| Symbol | LRRC10B |
|---|---|
| Full Name | Leucine Rich Repeat Containing 10B |
| Gene Type | protein-coding |
| Chromosomal Location | 11p15.4 |
| NCBI Gene ID | 100130417 ncbi.nlm.nih.gov/gene/100130417 |
| Ensembl ID | ENSG00000205730 |
| UniProt ID | A6NIK2 |
| OMIM ID | Not assigned |
| HGNC ID | 37219 |
| Aliases | MGC16384, FLJ39616 |
Description
LRRC10B (Leucine Rich Repeat Containing 10B) is a protein-coding gene located on chromosome 11p15.4. The encoded protein contains leucine-rich repeats, which are typically involved in protein-protein interactions. The specific biological function of LRRC10B remains largely uncharacterized, and no disease associations have been firmly established in curated databases.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No curated disease associations | Not established | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.5 | Low |
| Thyroid | 0.3 | Low |
| Adipose tissue | 0.2 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK 293 | 0.1 | Low expression |
| K562 | 0.0 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The LRRC10B protein (UniProt A6NIK2) is predicted to contain leucine-rich repeats, suggesting a role in protein-protein interactions. Its molecular function and cellular localization are not experimentally characterized. No structural or functional domains beyond the leucine-rich repeat motif have been annotated.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| LRRC10B Knockout HEK293 Cell Line | EDJ-KQ14118 | Human | 390205 | Details Get a Quote |
| LRRC10B Knockout HeLa Cell Line | EDJ-KQ60157 | Human | 390205 | Details Get a Quote |
| LRRC10B Knockout A-549 Cell Line | EDJ-KQ68618 | Human | 390205 | Details Get a Quote |
| LRRC10B Knockout HCT 116 Cell Line | EDJ-KQ76987 | Human | 390205 | Details Get a Quote |
